Urinary Microbiome Changes Following Administration of 500 mg of NDS-446 in Women With Dry OAB at 12 Weeks - a Single-center Study
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
The purpose of this study is to learn about how the use of 500 mg of dried cranberry powder extract (NDS-446) changes the bacteria that normal reside in the bladder of women who don't have urinary leakage problems but do have problems with urinary urgency and frequency.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 99
Healthy Volunteers: f
View:
• 18 years, female, ambulatory
• OAB symptoms \> 6 months
• Voiding frequency \> 8 times in 24 hrs and \> 3 episodes of urgency (grade 3 or 4) without incontinence during 3-day diary at baseline
Locations
United States
Illinois
Loyola Medical Center
RECRUITING
Maywood
Contact Information
Primary
Mary Tulke, RN
mtulke@luc.edu
708-216-2186
Backup
Elizabeth Mueller, MD
emuelle@lumc.edu
708-216-2170
Time Frame
Start Date: 2023-01-01
Estimated Completion Date: 2025-12-01
Participants
Target number of participants: 40
Treatments
Other: Intervention Group
All participants will receive 500 mg NDS-446 daily for 12 weeks
Related Therapeutic Areas
Sponsors
Leads: Loyola University